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Rapid detection of colistin resistance protein MCR-1 by LC–MS/MS

BACKGROUND: Colistin (polymyxin E) and polymixin B are important bactericidal antibiotics used in the treatment of serious infections caused by multi-drug resistant Gram-negative organisms. Transferrable plasmid-mediated colistin resistance, conferred by the product of the mcr-1 gene, has emerged as...

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Detalles Bibliográficos
Autores principales: Wang, Honghui, Chen, Yong, Strich, Jeffrey R., Drake, Steven K., Youn, Jung-Ho, Rosenberg, Avi Z., Gucek, Marjan, McGann, Patrick T., Suffredini, Anthony F., Dekker, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390366/
https://www.ncbi.nlm.nih.gov/pubmed/30890899
http://dx.doi.org/10.1186/s12014-019-9228-2