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FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21
BACKGROUND: Deregulation of ubiquitin ligases is related to the malignant progression of human cancers. F-box only protein 22 (FBXO22), an F-box E3 ligase, is a member of the F-box protein family. However, the biological function of FBXO22 in HCC and the underlying molecular mechanisms are still unc...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390379/ https://www.ncbi.nlm.nih.gov/pubmed/30808376 http://dx.doi.org/10.1186/s13046-019-1058-6 |