FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21

BACKGROUND: Deregulation of ubiquitin ligases is related to the malignant progression of human cancers. F-box only protein 22 (FBXO22), an F-box E3 ligase, is a member of the F-box protein family. However, the biological function of FBXO22 in HCC and the underlying molecular mechanisms are still unc...

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Detalles Bibliográficos
Autores principales: Zhang, Long, Chen, Jin, Ning, Deng, Liu, Qiumeng, Wang, Chao, Zhang, Zhaoqi, Chu, Liang, Yu, Chengpeng, Liang, Hui-fang, Zhang, Bixiang, Chen, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390379/
https://www.ncbi.nlm.nih.gov/pubmed/30808376
http://dx.doi.org/10.1186/s13046-019-1058-6

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