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‘Second-generation’ 1,2,3-triazole-based inhibitors of Porphyromonas gingivalis adherence to oral streptococci and biofilm formation

Several ‘second-generation’ click inhibitors of the multi-species biofilm propagated by the adherence of the oral pathogen Porphyromonas gingivalis to Streptococcus gordonii were synthesized and evaluated. The design of the structures was based on the results obtained with the first-generation diphe...

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Detalles Bibliográficos
Autores principales: Patil, Pravin C., Tan, Jinlian, Demuth, Donald R., Luzzio, Frederick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390472/
https://www.ncbi.nlm.nih.gov/pubmed/30881614
http://dx.doi.org/10.1039/c8md00405f