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Predicting protein-ligand binding residues with deep convolutional neural networks

BACKGROUND: Ligand-binding proteins play key roles in many biological processes. Identification of protein-ligand binding residues is important in understanding the biological functions of proteins. Existing computational methods can be roughly categorized as sequence-based or 3D-structure-based met...

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Detalles Bibliográficos
Autores principales: Cui, Yifeng, Dong, Qiwen, Hong, Daocheng, Wang, Xikun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390579/
https://www.ncbi.nlm.nih.gov/pubmed/30808287
http://dx.doi.org/10.1186/s12859-019-2672-1