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Zoledronic acid blocks the interaction between breast cancer cells and regulatory T-cells

BACKGROUND: Zoledronic acid (ZA), a nitrogen-containing bisphosphonate, inhibits osteoclastogenesis. Emerging evidence suggests that ZA has anti-tumor and anti-metastatic properties for breast cancer cells. In a mouse model of ZA-related osteonecrosis of the jaw, ZA administration was found to suppr...

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Detalles Bibliográficos
Autores principales: Liu, Hsien, Wang, Shih-Han, Chen, Shin-Cheh, Chen, Ching-Ying, Lin, Tsun-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390606/
https://www.ncbi.nlm.nih.gov/pubmed/30808421
http://dx.doi.org/10.1186/s12885-019-5379-9