Cargando…
Zoledronic acid blocks the interaction between breast cancer cells and regulatory T-cells
BACKGROUND: Zoledronic acid (ZA), a nitrogen-containing bisphosphonate, inhibits osteoclastogenesis. Emerging evidence suggests that ZA has anti-tumor and anti-metastatic properties for breast cancer cells. In a mouse model of ZA-related osteonecrosis of the jaw, ZA administration was found to suppr...
Autores principales: | Liu, Hsien, Wang, Shih-Han, Chen, Shin-Cheh, Chen, Ching-Ying, Lin, Tsun-Mei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390606/ https://www.ncbi.nlm.nih.gov/pubmed/30808421 http://dx.doi.org/10.1186/s12885-019-5379-9 |
Ejemplares similares
-
Immune modulation of CD4(+)CD25(+) regulatory T cells by zoledronic acid
por: Liu, Hsien, et al.
Publicado: (2016) -
In vitro synergistic cytoreductive effects of zoledronic acid and radiation on breast cancer cells
por: Ural, A Ugur, et al.
Publicado: (2006) -
Pretreatment of breast cancer cells with doxorubicin facilitates the subsequent uptake of zoledronic acid
por: Lefley, DV, et al.
Publicado: (2008) -
Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion
por: Rietkötter, Eva, et al.
Publicado: (2013) -
Human stromal cells are required for an anti-breast cancer effect of zoledronic acid
por: Nienhuis, Hilde H., et al.
Publicado: (2015)