The antifibrotic drug pirfenidone inhibits spondyloarthritis fibroblast-like synoviocytes and osteoblasts in vitro

BACKGROUND: The pathogenesis of spondyloarthritis (SpA) involves both inflammation and new bone formation in the spine. In line with this, the disease has been characterized as both inflammatory and fibrotic. The current treatment dampens inflammation while new bone formation can progress. Therefore...

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Detalles Bibliográficos
Autores principales: Stougaard, Julie, Lomholt, Søren, Ommen, Pernille, Kelsen, Jens, Kragstrup, Tue W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390625/
https://www.ncbi.nlm.nih.gov/pubmed/30886983
http://dx.doi.org/10.1186/s41927-018-0040-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390625/
https://www.ncbi.nlm.nih.gov/pubmed/30886983
http://dx.doi.org/10.1186/s41927-018-0040-9

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