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Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system

BACKGROUND: Indian hedgehog (IHH) and Sonic hedgehog (SHH) are important regulators of chondrogenesis. However, activation of IHH and SHH also promotes chondrocyte hypertrophy and ossification during chondrogenesis. The aims of this study were to investigate the effect of microgravity on IHH- and SH...

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Detalles Bibliográficos
Autores principales: Chen, Liyang, Liu, Gejun, Li, Wenjun, Wu, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390628/
https://www.ncbi.nlm.nih.gov/pubmed/30858866
http://dx.doi.org/10.1186/s11658-019-0144-2