Enrichment post-library preparation enhances the sensitivity of high-throughput sequencing-based detection and characterization of viruses from complex samples

BACKGROUND: Sequencing-based detection and characterization of viruses in complex samples can suffer from lack of sensitivity due to a variety of factors including, but not limited to, low titer, small genome size, and contribution of host or environmental nucleic acids. Hybridization-based target e...

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Detalles Bibliográficos
Autores principales: Paskey, Adrian C., Frey, Kenneth G., Schroth, Gary, Gross, Stephen, Hamilton, Theron, Bishop-Lilly, Kimberly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390631/
https://www.ncbi.nlm.nih.gov/pubmed/30808306
http://dx.doi.org/10.1186/s12864-019-5543-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390631/
https://www.ncbi.nlm.nih.gov/pubmed/30808306
http://dx.doi.org/10.1186/s12864-019-5543-2

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