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Enrichment post-library preparation enhances the sensitivity of high-throughput sequencing-based detection and characterization of viruses from complex samples
BACKGROUND: Sequencing-based detection and characterization of viruses in complex samples can suffer from lack of sensitivity due to a variety of factors including, but not limited to, low titer, small genome size, and contribution of host or environmental nucleic acids. Hybridization-based target e...
Autores principales: | Paskey, Adrian C., Frey, Kenneth G., Schroth, Gary, Gross, Stephen, Hamilton, Theron, Bishop-Lilly, Kimberly A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390631/ https://www.ncbi.nlm.nih.gov/pubmed/30808306 http://dx.doi.org/10.1186/s12864-019-5543-2 |
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