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Tetrafluoropyridyl (TFP): a general phenol protecting group readily cleaved under mild conditions

Phenols are extremely valuable building blocks in the areas of pharmaceuticals, natural products, materials and catalysts. In order to carry out modifications on phenols, the phenolic oxygen is routinely protected to prevent unwanted side reactions. Presently many of the protecting groups available...

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Detalles Bibliográficos
Autores principales: Brittain, William D. G., Cobb, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390695/
https://www.ncbi.nlm.nih.gov/pubmed/30623945
http://dx.doi.org/10.1039/c8ob02899k