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β2-Adrenoceptors and GRK2 as Potential Biomarkers in Patients With Chronic Pulmonary Regurgitation

Pulmonary regurgitation (PR) is a frequent complication after repair of congenital heart disease. Three different GRK isoforms (GRK2, GRK5, and GRK3) and two β-adrenoceptors (β1-AR and β2-AR) are present in peripheral blood mononuclear cells (PBMC) and their expression changes as a consequence of th...

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Detalles Bibliográficos
Autores principales: Rodriguez-Serrano, María, Rueda, Joaquín, Buendía, Francisco, Monto, Fermi, Aguero, Jaime, Osa, Ana, Cano, Oscar, Martínez-Dolz, Luis, D’Ocon, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390728/
https://www.ncbi.nlm.nih.gov/pubmed/30837872
http://dx.doi.org/10.3389/fphar.2019.00093