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Clinical efficacy of new JAK inhibitors under development. Just more of the same?

Janus kinase inhibition is promising in the treatment of RA, with already two oral drugs marketed. New compounds are under investigation that are more selective for Janus kinase 1 or Janus kinase 3. Phase II results for filgotinib, upadacitinib, peficitinib and decernotinib are reviewed showing almo...

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Detalles Bibliográficos
Autor principal: Westhovens, Rene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390876/
https://www.ncbi.nlm.nih.gov/pubmed/30806706
http://dx.doi.org/10.1093/rheumatology/key256