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Clinical efficacy of new JAK inhibitors under development. Just more of the same?
Janus kinase inhibition is promising in the treatment of RA, with already two oral drugs marketed. New compounds are under investigation that are more selective for Janus kinase 1 or Janus kinase 3. Phase II results for filgotinib, upadacitinib, peficitinib and decernotinib are reviewed showing almo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390876/ https://www.ncbi.nlm.nih.gov/pubmed/30806706 http://dx.doi.org/10.1093/rheumatology/key256 |