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Time-dependent Pax3-mediated chromatin remodeling and cooperation with Six4 and Tead2 specify the skeletal myogenic lineage in developing mesoderm

The transcriptional mechanisms driving lineage specification during development are still largely unknown, as the interplay of multiple transcription factors makes it difficult to dissect these molecular events. Using a cell-based differentiation platform to probe transcription function, we investig...

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Detalles Bibliográficos
Autores principales: Magli, Alessandro, Baik, June, Mills, Lauren J., Kwak, Il-Youp, Dillon, Bridget S., Mondragon Gonzalez, Ricardo, Stafford, David A., Swanson, Scott A., Stewart, Ron, Thomson, James A., Garry, Daniel J., Dynlacht, Brian D., Perlingeiro, Rita C. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390996/
https://www.ncbi.nlm.nih.gov/pubmed/30807574
http://dx.doi.org/10.1371/journal.pbio.3000153