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Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway

Expulsion of parasitic gastrointestinal nematodes requires diverse effector mechanisms coordinated by a Th2-type response. The evolutionarily conserved JmjC protein; Myc Induced Nuclear Antigen (Mina) has been shown to repress IL4, a key Th2 cytokine, suggesting Mina may negatively regulate nematode...

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Detalles Bibliográficos
Autores principales: Pillai, Meenu R., Mihi, Belgacem, Ishiwata, Kenji, Nakamura, Kiminori, Sakuragi, Naoya, Finkelstein, David B., McGargill, Maureen A., Nakayama, Toshinori, Ayabe, Tokiyoshi, Coleman, Mathew L., Bix, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391002/
https://www.ncbi.nlm.nih.gov/pubmed/30807587
http://dx.doi.org/10.1371/journal.pone.0211244