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Role of smooth muscle cell p53 in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is characterized by remodeling and narrowing of the pulmonary arteries, which lead to elevation of right ventricular pressure, heart failure, and death. Proliferation of pulmonary artery smooth muscle cells (PASMCs) is thought to be central to the pathogenesis o...

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Detalles Bibliográficos
Autores principales: Wakasugi, Takayuki, Shimizu, Ippei, Yoshida, Yohko, Hayashi, Yuka, Ikegami, Ryutaro, Suda, Masayoshi, Katsuumi, Goro, Nakao, Masaaki, Hoyano, Makoto, Kashimura, Takeshi, Nakamura, Kazufumi, Ito, Hiroshi, Nojiri, Takashi, Soga, Tomoyoshi, Minamino, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391010/
https://www.ncbi.nlm.nih.gov/pubmed/30807606
http://dx.doi.org/10.1371/journal.pone.0212889