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Long noncoding RNAs: p53’s secret weapon in the fight against cancer?

p53 regulates the expression of hundreds of genes. Recent surprising observations indicate that no single protein-coding gene controls the tumor suppressor effects of p53. This raises the possibility that a subset of these genes, regulated by a p53-induced long noncoding RNA (lncRNA), could control...

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Detalles Bibliográficos
Autores principales: Dangelmaier, Emily, Lazar, Sarah B., Lal, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391031/
https://www.ncbi.nlm.nih.gov/pubmed/30759134
http://dx.doi.org/10.1371/journal.pbio.3000143