A chemoenzymatically synthesized cholesterol-g-poly(amine-co-ester)-mediated p53 gene delivery for achieving antitumor efficacy in prostate cancer

BACKGROUND: An amphiphilic cationic copolymer cholesterol-g-poly(amine-co-ester), namely Chol-g-PMSC-PPDL synthesized in a chemoenzymatic route has been utilized as a carrier for p53 gene delivery to check its antitumor efficacy, using human prostate cancer cell line PC-3 (p53 null) as a model. MATE...

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Detalles Bibliográficos
Autores principales: Dong, Mengmeng, Chen, Jiawen, Zhang, Jiayuan, Liang, Xiao, Yang, Jiebing, Li, Dan, Li, Quanshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391147/
https://www.ncbi.nlm.nih.gov/pubmed/30863051
http://dx.doi.org/10.2147/IJN.S191905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391147/
https://www.ncbi.nlm.nih.gov/pubmed/30863051
http://dx.doi.org/10.2147/IJN.S191905

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