siRNA-based breast cancer therapy by suppressing 17β-hydroxysteroid dehydrogenase type 1 in an optimized xenograft cell and molecular biology model in vivo

PURPOSE: Hormone-dependent breast cancer is the most common form of breast cancer, and inhibiting 17β-HSD1 can play an attractive role in decreasing estrogen and cancer cell proliferation. However, the majority of existing inhibitors have been developed from estrogens and inevitably possess residual...

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Detalles Bibliográficos
Autores principales: Li, Fang, Zhu, ZhiHan, Xue, Man, He, WanHong, Zhang, Ting, Feng, LingLin, Lin, ShengXiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391152/
https://www.ncbi.nlm.nih.gov/pubmed/30863015
http://dx.doi.org/10.2147/DDDT.S180836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391152/
https://www.ncbi.nlm.nih.gov/pubmed/30863015
http://dx.doi.org/10.2147/DDDT.S180836

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