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D-α-tocopherol polyethylene glycol 1000 succinate-modified liposomes with an siRNA corona confer enhanced cellular uptake and targeted delivery of doxorubicin via tumor priming

BACKGROUND: Combination therapy employing siRNAs and antitumor drugs is a promising method for the treatment of solid tumors. However, regarding combined treatments involving siRNAs and chemotherapeutic reagents, most prior research has focused on the enhanced cytotoxicity against tumor cells confer...

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Detalles Bibliográficos
Autores principales: Tan, Xi, Fang, Yan, Ren, Yuanyuan, Li, Yinghuan, Wu, Peicheng, Yang, Xiangliang, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391153/
https://www.ncbi.nlm.nih.gov/pubmed/30863058
http://dx.doi.org/10.2147/IJN.S191858