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Synergy from gene expression and network mining (SynGeNet) method predicts synergistic drug combinations for diverse melanoma genomic subtypes

Systems biology perspectives are crucial for understanding the pathophysiology of complex diseases, and therefore hold great promise for the discovery of novel treatment strategies. Drug combinations have been shown to improve durability and reduce resistance to available first-line therapies in a v...

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Detalles Bibliográficos
Autores principales: Regan-Fendt, Kelly E., Xu, Jielin, DiVincenzo, Mallory, Duggan, Megan C., Shakya, Reena, Na, Ryejung, Carson, William E., Payne, Philip R. O., Li, Fuhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391384/
https://www.ncbi.nlm.nih.gov/pubmed/30820351
http://dx.doi.org/10.1038/s41540-019-0085-4