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Synergy from gene expression and network mining (SynGeNet) method predicts synergistic drug combinations for diverse melanoma genomic subtypes
Systems biology perspectives are crucial for understanding the pathophysiology of complex diseases, and therefore hold great promise for the discovery of novel treatment strategies. Drug combinations have been shown to improve durability and reduce resistance to available first-line therapies in a v...
Autores principales: | Regan-Fendt, Kelly E., Xu, Jielin, DiVincenzo, Mallory, Duggan, Megan C., Shakya, Reena, Na, Ryejung, Carson, William E., Payne, Philip R. O., Li, Fuhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391384/ https://www.ncbi.nlm.nih.gov/pubmed/30820351 http://dx.doi.org/10.1038/s41540-019-0085-4 |
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