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Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth

Despite a growing body of knowledge about the genomic landscape and molecular pathogenesis of sarcomas, translation of basic discoveries into targeted therapies and significant clinical gains has remained elusive. Renewed interest in altered metabolic properties of cancer cells has led to an explora...

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Detalles Bibliográficos
Autores principales: Issaq, Sameer H., Mendoza, Arnulfo, Fox, Stephen D., Helman, Lee J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391386/
https://www.ncbi.nlm.nih.gov/pubmed/30808861
http://dx.doi.org/10.1038/s41389-019-0129-z