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Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth
Despite a growing body of knowledge about the genomic landscape and molecular pathogenesis of sarcomas, translation of basic discoveries into targeted therapies and significant clinical gains has remained elusive. Renewed interest in altered metabolic properties of cancer cells has led to an explora...
Autores principales: | Issaq, Sameer H., Mendoza, Arnulfo, Fox, Stephen D., Helman, Lee J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391386/ https://www.ncbi.nlm.nih.gov/pubmed/30808861 http://dx.doi.org/10.1038/s41389-019-0129-z |
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