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Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury
ATP depletion and succinate accumulation during ischemia lead to oxidative damage to mammalian organs upon reperfusion. In contrast, freshwater turtles survive weeks of anoxia at low temperatures without suffering from oxidative damage upon reoxygenation, but the mechanisms are unclear. To determine...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391391/ https://www.ncbi.nlm.nih.gov/pubmed/30808950 http://dx.doi.org/10.1038/s41598-019-39836-5 |