Mesalamine and azathioprine modulate junctional complexes and restore epithelial barrier function in intestinal inflammation

Disruption of mucosal structure and barrier function contribute to the pathogenesis of inflammatory bowel disease (IBD). Efficacy of therapy in IBD is based on endoscopic mucosal healing, which occurs by a dynamic interplay of epithelial cell regeneration, migration and differentiation. Both mesalam...

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Detalles Bibliográficos
Autores principales: Khare, Vineeta, Krnjic, Anita, Frick, Adrian, Gmainer, Christina, Asboth, Mario, Jimenez, Kristine, Lang, Michaela, Baumgartner, Maximilian, Evstatiev, Rayko, Gasche, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391397/
https://www.ncbi.nlm.nih.gov/pubmed/30809073
http://dx.doi.org/10.1038/s41598-019-39401-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391397/
https://www.ncbi.nlm.nih.gov/pubmed/30809073
http://dx.doi.org/10.1038/s41598-019-39401-0

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