Cargando…
Mesalamine and azathioprine modulate junctional complexes and restore epithelial barrier function in intestinal inflammation
Disruption of mucosal structure and barrier function contribute to the pathogenesis of inflammatory bowel disease (IBD). Efficacy of therapy in IBD is based on endoscopic mucosal healing, which occurs by a dynamic interplay of epithelial cell regeneration, migration and differentiation. Both mesalam...
Autores principales: | Khare, Vineeta, Krnjic, Anita, Frick, Adrian, Gmainer, Christina, Asboth, Mario, Jimenez, Kristine, Lang, Michaela, Baumgartner, Maximilian, Evstatiev, Rayko, Gasche, Christoph |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391397/ https://www.ncbi.nlm.nih.gov/pubmed/30809073 http://dx.doi.org/10.1038/s41598-019-39401-0 |
Ejemplares similares
-
The food additive EDTA aggravates colitis and colon carcinogenesis in mouse models
por: Evstatiev, Rayko, et al.
Publicado: (2021) -
A Novel PAK1–Notch1 Axis Regulates Crypt Homeostasis in Intestinal Inflammation
por: Frick, Adrian, et al.
Publicado: (2020) -
Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1
por: Khare, Vineeta, et al.
Publicado: (2013) -
Overexpression of PAK1 Promotes Cell Survival in Inflammatory Bowel Diseases and Colitis-associated Cancer
por: Khare, Vineeta, et al.
Publicado: (2015) -
An Intracytoplasmic IL-10 Receptor Variant Permits Rapid Reduction in STAT3 Activation
por: Finsterbusch, Michaela, et al.
Publicado: (2011)