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Phosphorylation Changes in Response to Kinase Inhibitor H89 in PKA-Null Cells

Protein phosphorylation, mediated by protein kinases, plays a crucial role in cellular regulation. One of the most important protein kinases is protein kinase A (PKA). N-[2-p-bromocinnamylamino-ethyl]-5-isoquinolinesulphonamide (H89) is often used as a “PKA specific inhibitor” to study the involveme...

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Detalles Bibliográficos
Autores principales: Limbutara, Kavee, Kelleher, Andrew, Yang, Chin-Rang, Raghuram, Viswanathan, Knepper, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391403/
https://www.ncbi.nlm.nih.gov/pubmed/30808967
http://dx.doi.org/10.1038/s41598-019-39116-2