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Repeated neonatal isoflurane exposures in the mouse induce apoptotic degenerative changes in the brain and relatively mild long-term behavioral deficits

Epidemiological studies suggest exposures to anesthetic agents and/or sedative drugs (AASDs) in children under three years old, or pregnant women during the third trimester, may adversely affect brain development. Evidence suggests lengthy or repeated AASD exposures are associated with increased ris...

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Detalles Bibliográficos
Autores principales: Maloney, Susan E., Yuede, Carla M., Creeley, Catherine E., Williams, Sasha L., Huffman, Jacob N., Taylor, George T., Noguchi, Kevin N., Wozniak, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391407/
https://www.ncbi.nlm.nih.gov/pubmed/30808927
http://dx.doi.org/10.1038/s41598-019-39174-6