Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells

Mammalian target of rapamycin (mTOR) is a central regulator of cellular metabolism. The importance of mTORC1 signaling in neuronal development and functions has been highlighted by its strong relationship with many neurological and neuropsychiatric diseases. Previous studies demonstrated that hypera...

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Detalles Bibliográficos
Autores principales: Sakai, Yusuke, Kassai, Hidetoshi, Nakayama, Hisako, Fukaya, Masahiro, Maeda, Tatsuya, Nakao, Kazuki, Hashimoto, Kouichi, Sakagami, Hiroyuki, Kano, Masanobu, Aiba, Atsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391425/
https://www.ncbi.nlm.nih.gov/pubmed/30808980
http://dx.doi.org/10.1038/s41598-019-38730-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391425/
https://www.ncbi.nlm.nih.gov/pubmed/30808980
http://dx.doi.org/10.1038/s41598-019-38730-4

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