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Elevated IgM and abnormal free light chain ratio are increased in relatives from high-risk chronic lymphocytic leukemia pedigrees

Abnormal serum immunoglobulin (Ig) free light chains (FLC) are established biomarkers of early disease in multiple B-cell lymphoid malignancies, including chronic lymphocytic leukemia (CLL). Heavy chains have also been shown to be biomarkers in plasma cell disorders. An unanswered question is whethe...

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Detalles Bibliográficos
Autores principales: Glenn, Martha J., Madsen, Michael J., Davis, Ethan, Garner, Cassandra D., Curtin, Karen, Jones, Brandt, Williams, Justin A., Tomasson, Michael H., Camp, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391432/
https://www.ncbi.nlm.nih.gov/pubmed/30808891
http://dx.doi.org/10.1038/s41408-019-0186-8