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Directed Differentiation of Human Pluripotent Stem Cells to Podocytes under Defined Conditions

A major cause of chronic kidney disease (CKD) is glomerular disease, which can be attributed to a spectrum of podocyte disorders. Podocytes are non-proliferative, terminally differentiated cells. Thus, the limited supply of primary podocytes impedes CKD research. Differentiation of human pluripotent...

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Detalles Bibliográficos
Autores principales: Qian, Tongcheng, Hernday, Shaenah E., Bao, Xiaoping, Olson, William R., Panzer, Sarah E., Shusta, Eric V., Palecek, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391455/
https://www.ncbi.nlm.nih.gov/pubmed/30808965
http://dx.doi.org/10.1038/s41598-019-39504-8