Cargando…

Directed Differentiation of Human Pluripotent Stem Cells to Podocytes under Defined Conditions

A major cause of chronic kidney disease (CKD) is glomerular disease, which can be attributed to a spectrum of podocyte disorders. Podocytes are non-proliferative, terminally differentiated cells. Thus, the limited supply of primary podocytes impedes CKD research. Differentiation of human pluripotent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qian, Tongcheng, Hernday, Shaenah E., Bao, Xiaoping, Olson, William R., Panzer, Sarah E., Shusta, Eric V., Palecek, Sean P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391455/ https://www.ncbi.nlm.nih.gov/pubmed/30808965 http://dx.doi.org/10.1038/s41598-019-39504-8

Ejemplares similares

Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells
por: Qian, Tongcheng, et al.
Publicado: (2017)

Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions
por: Bao, Xiaoping, et al.
Publicado: (2016)

Human pluripotent stem cell‐derived epicardial progenitors can differentiate to endocardial‐like endothelial cells
por: Bao, Xiaoping, et al.
Publicado: (2017)

Commentary on human pluripotent stem cell-based blood–brain barrier models
por: Lippmann, Ethan S., et al.
Publicado: (2020)

Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling
por: Lian, Xiaojun, et al.
Publicado: (2014)

Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling
por: Lian, Xiaojun, et al.
Publicado: (2015)

Directed differentiation of human pluripotent stem cells to epicardial-derived fibroblasts
por: Floy, Martha E., et al.
Publicado: (2022)

Exploring the effects of cell seeding density on the differentiation of human pluripotent stem cells to brain microvascular endothelial cells
por: Wilson, Hannah K, et al.
Publicado: (2015)

Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions
por: Nishihara, Hideaki, et al.
Publicado: (2021)

Human Blood-Brain Barrier Endothelial Cells Derived from Pluripotent Stem Cells
por: Lippmann, Ethan S., et al.
Publicado: (2012)

Three-dimensional system enabling the maintenance and directed differentiation of pluripotent stem cells under defined conditions
por: Zujur, Denise, et al.
Publicado: (2017)

Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
por: Gastfriend, Benjamin D, et al.
Publicado: (2021)

An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons
por: Canfield, Scott G., et al.
Publicado: (2019)

Correction to: An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons
por: Canfield, Scott G., et al.
Publicado: (2019)

Directed Differentiation of Human Pluripotent Stem Cells towards Corneal Endothelial-Like Cells under Defined Conditions
por: Grönroos, Pyry, et al.
Publicado: (2021)

A Small Molecule Inhibitor of Src Family Kinases Promotes Simple Epithelial Differentiation of Human Pluripotent Stem Cells
por: Lian, Xiaojun, et al.
Publicado: (2013)

Modeling Group B Streptococcus and Blood-Brain Barrier Interaction by Using Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells
por: Kim, Brandon J., et al.
Publicado: (2017)

Modeling the blood–brain barrier using stem cell sources
por: Lippmann, Ethan S, et al.
Publicado: (2013)

Accelerated protocol for the differentiation of podocytes from human pluripotent stem cells
por: Bejoy, Julie, et al.
Publicado: (2021)

Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties
por: Stebbins, Matthew J., et al.
Publicado: (2019)

Advancing human induced pluripotent stem cell‐derived blood‐brain barrier models for studying immune cell interactions
por: Nishihara, Hideaki, et al.
Publicado: (2020)

Generation of functional podocytes from human induced pluripotent stem cells
por: Ciampi, Osele, et al.
Publicado: (2016)

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources
por: Lippmann, Ethan S., et al.
Publicado: (2014)

Cardiac differentiation of human pluripotent stem cells using defined extracellular matrix proteins reveals essential role of fibronectin
por: Zhang, Jianhua, et al.
Publicado: (2022)

Metabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes
por: Bhute, Vijesh J., et al.
Publicado: (2017)

Efficient Generation of Functional Dopaminergic Neurons from Human Induced Pluripotent Stem Cells Under Defined Conditions
por: Swistowski, Andrzej, et al.
Publicado: (2010)

Generation of stable integration‐free pig induced pluripotent stem cells under chemically defined culture condition
por: Zhu, Qianqian, et al.
Publicado: (2023)

Efficient, Long Term Production of Monocyte-Derived Macrophages from Human Pluripotent Stem Cells under Partly-Defined and Fully-Defined Conditions
por: van Wilgenburg, Bonnie, et al.
Publicado: (2013)

Role of Arginase-II in Podocyte Injury under Hypoxic Conditions
por: Ren, Zhilong, et al.
Publicado: (2022)

Podocytes derived from human induced pluripotent stem cells: characterization, comparison, and modeling of diabetic kidney disease
por: Bejoy, Julie, et al.
Publicado: (2022)

Efficient generation of region-specific forebrain neurons from human pluripotent stem cells under highly defined condition
por: Yuan, Fang, et al.
Publicado: (2015)

Defining the Molecular Character of the Developing and Adult Kidney Podocyte
por: Brunskill, Eric W., et al.
Publicado: (2011)

Under the right conditions: protecting podocytes from diabetes-induced damage
por: Ali, Imran HA, et al.
Publicado: (2013)

Modelling X-linked Alport Syndrome With Induced Pluripotent Stem Cell-Derived Podocytes
por: Lau, Ricky Wai Kiu, et al.
Publicado: (2021)

Differentiation of Cardiomyocytes from Human Pluripotent Stem Cells in Fully Chemically Defined Conditions
por: Lin, Yongshun, et al.
Publicado: (2020)

Chemically defined and xeno-free culture condition for human extended pluripotent stem cells
por: Liu, Bei, et al.
Publicado: (2021)

Reduction of N-Glycolylneuraminic Acid in Human Induced Pluripotent Stem Cells Generated or Cultured under Feeder- and Serum-Free Defined Conditions
por: Hayashi, Yohei, et al.
Publicado: (2010)

α-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal
por: Laperle, Alex, et al.
Publicado: (2015)

Small Molecule-Assisted, Line-Independent Maintenance of Human Pluripotent Stem Cells in Defined Conditions
por: Frank, Stefan, et al.
Publicado: (2012)

Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition
por: Kirino, Kosuke, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tv1qh3h8v426dehi1pnacrfj2b