Quantitative sensing and signalling of single-stranded DNA during the DNA damage response

The DNA damage checkpoint senses the presence of DNA lesions and controls the cellular response thereto. A crucial DNA damage signal is single-stranded DNA (ssDNA), which is frequently found at sites of DNA damage and recruits the sensor checkpoint kinase Mec1-Ddc2. However, how this signal – and th...

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Detalles Bibliográficos
Autores principales: Bantele, Susanne C. S., Lisby, Michael, Pfander, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391461/
https://www.ncbi.nlm.nih.gov/pubmed/30808869
http://dx.doi.org/10.1038/s41467-019-08889-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391461/
https://www.ncbi.nlm.nih.gov/pubmed/30808869
http://dx.doi.org/10.1038/s41467-019-08889-5

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