A novel mechanism for the protection of embryonic stem cell derived tenocytes from inflammatory cytokine interleukin 1 beta

Interleukin 1β (IL-1β) is upregulated following tendon injury. Here we demonstrate that in adult and fetal tenocytes IL-1β increases the expression of matrix metalloproteinases, tenascin-C and Sox9 and decreases the expression of scleraxis and cartilage oligomeric matrix protein. When cultured in 3-...

Descripción completa

Detalles Bibliográficos
Autores principales: McClellan, Alyce, Evans, Richard, Sze, Cheryl, Kan, Shohei, Paterson, Yasmin, Guest, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391488/
https://www.ncbi.nlm.nih.gov/pubmed/30808942
http://dx.doi.org/10.1038/s41598-019-39370-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391488/
https://www.ncbi.nlm.nih.gov/pubmed/30808942
http://dx.doi.org/10.1038/s41598-019-39370-4

Ejemplares similares