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A novel mechanism for the protection of embryonic stem cell derived tenocytes from inflammatory cytokine interleukin 1 beta
Interleukin 1β (IL-1β) is upregulated following tendon injury. Here we demonstrate that in adult and fetal tenocytes IL-1β increases the expression of matrix metalloproteinases, tenascin-C and Sox9 and decreases the expression of scleraxis and cartilage oligomeric matrix protein. When cultured in 3-...
Autores principales: | McClellan, Alyce, Evans, Richard, Sze, Cheryl, Kan, Shohei, Paterson, Yasmin, Guest, Deborah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391488/ https://www.ncbi.nlm.nih.gov/pubmed/30808942 http://dx.doi.org/10.1038/s41598-019-39370-4 |
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