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Trophoblast-Specific Expression of Hif-1α Results in Preeclampsia-Like Symptoms and Fetal Growth Restriction

The placenta is an essential organ that is formed during pregnancy and its proper development is critical for embryonic survival. While several animal models have been shown to exhibit some of the pathological effects present in human preeclampsia, these models often do not represent the physiologic...

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Detalles Bibliográficos
Autores principales: Albers, Renee E., Kaufman, Melissa R., Natale, Bryony V., Keoni, Chanel, Kulkarni-Datar, Kashmira, Min, Sarah, Williams, Clintoria R., Natale, David R. C., Brown, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391498/
https://www.ncbi.nlm.nih.gov/pubmed/30808910
http://dx.doi.org/10.1038/s41598-019-39426-5