Pressure Reveals Unique Conformational Features in Prion Protein Fibril Diversity

The prion protein (PrP) misfolds and assembles into a wide spectrum of self-propagating quaternary structures, designated PrP(Sc). These various PrP superstructures can be functionally different, conferring clinically distinctive symptomatology, neuropathology and infectious character to the associa...

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Detalles Bibliográficos
Autores principales: Torrent, Joan, Martin, Davy, Noinville, Sylvie, Yin, Yi, Doumic, Marie, Moudjou, Mohammed, Béringue, Vincent, Rezaei, Human
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391531/
https://www.ncbi.nlm.nih.gov/pubmed/30808892
http://dx.doi.org/10.1038/s41598-019-39261-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391531/
https://www.ncbi.nlm.nih.gov/pubmed/30808892
http://dx.doi.org/10.1038/s41598-019-39261-8

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