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Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis
As clinical evidence supports a negative impact of dysfunctional energy metabolism on the disease progression in amyotrophic lateral sclerosis, it is vital to understand how the energy metabolic pathways are altered and whether they can be restored to slow disease progression. Possible approaches in...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391613/ https://www.ncbi.nlm.nih.gov/pubmed/30698736 http://dx.doi.org/10.1093/brain/awy353 |