Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis

As clinical evidence supports a negative impact of dysfunctional energy metabolism on the disease progression in amyotrophic lateral sclerosis, it is vital to understand how the energy metabolic pathways are altered and whether they can be restored to slow disease progression. Possible approaches in...

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Detalles Bibliográficos
Autores principales: Allen, Scott P, Hall, Benjamin, Castelli, Lydia M, Francis, Laura, Woof, Ryan, Siskos, Alexandros P, Kouloura, Eirini, Gray, Elizabeth, Thompson, Alexander G, Talbot, Kevin, Higginbottom, Adrian, Myszczynska, Monika, Allen, Chloe F, Stopford, Matthew J, Hemingway, Jordan, Bauer, Claudia S, Webster, Christopher P, De Vos, Kurt J, Turner, Martin R, Keun, Hector C, Hautbergue, Guillaume M, Ferraiuolo, Laura, Shaw, Pamela J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391613/
https://www.ncbi.nlm.nih.gov/pubmed/30698736
http://dx.doi.org/10.1093/brain/awy353

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