Not all arrestins are created equal: Therapeutic implications of the functional diversity of the β-arrestins in the heart

The two ubiquitous, outside the retina, G protein-coupled receptor (GPCR) adapter proteins, β-arrestin-1 and -2 (also known as arrestin-2 and -3, respectively), have three major functions in cells: GPCR desensitization, i.e., receptor decoupling from G-proteins; GPCR internalization via clathrin-coa...

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Detalles Bibliográficos
Autores principales: Lymperopoulos, Anastasios, Wertz, Shelby L, Pollard, Celina M, Desimine, Victoria L, Maning, Jennifer, McCrink, Katie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391623/
https://www.ncbi.nlm.nih.gov/pubmed/30820275
http://dx.doi.org/10.4330/wjc.v11.i2.47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391623/
https://www.ncbi.nlm.nih.gov/pubmed/30820275
http://dx.doi.org/10.4330/wjc.v11.i2.47

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