IL-1β and TNFα Differentially Influence NF-κB Activity and FasL-Induced Apoptosis in Primary Murine Hepatocytes During LPS-Induced Inflammation

Macrophage-derived cytokines largely influence the behavior of hepatocytes during an inflammatory response. We previously reported that both TNFα and IL-1β, which are released by macrophages upon LPS stimulation, affect Fas ligand (FasL)-induced apoptotic signaling. Whereas TNFα preincubation leads...

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Detalles Bibliográficos
Autores principales: Rex, Julia, Lutz, Anna, Faletti, Laura E., Albrecht, Ute, Thomas, Maria, Bode, Johannes G., Borner, Christoph, Sawodny, Oliver, Merfort, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391654/
https://www.ncbi.nlm.nih.gov/pubmed/30842741
http://dx.doi.org/10.3389/fphys.2019.00117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391654/
https://www.ncbi.nlm.nih.gov/pubmed/30842741
http://dx.doi.org/10.3389/fphys.2019.00117

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