Cargando…

IL-1β and TNFα Differentially Influence NF-κB Activity and FasL-Induced Apoptosis in Primary Murine Hepatocytes During LPS-Induced Inflammation

Macrophage-derived cytokines largely influence the behavior of hepatocytes during an inflammatory response. We previously reported that both TNFα and IL-1β, which are released by macrophages upon LPS stimulation, affect Fas ligand (FasL)-induced apoptotic signaling. Whereas TNFα preincubation leads...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rex, Julia, Lutz, Anna, Faletti, Laura E., Albrecht, Ute, Thomas, Maria, Bode, Johannes G., Borner, Christoph, Sawodny, Oliver, Merfort, Irmgard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391654/ https://www.ncbi.nlm.nih.gov/pubmed/30842741 http://dx.doi.org/10.3389/fphys.2019.00117

Ejemplares similares

TNFα sensitizes hepatocytes to FasL-induced apoptosis by NFκB-mediated Fas upregulation
por: Faletti, Laura, et al.
Publicado: (2018)

Interleukin-1β Enhances FasL-Induced Caspase-3/-7 Activity without Increasing Apoptosis in Primary Mouse Hepatocytes
por: Lutz, Anna, et al.
Publicado: (2014)

Modeling the TNFα-Induced Apoptosis Pathway in Hepatocytes
por: Schlatter, Rebekka, et al.
Publicado: (2011)

Genome-wide comparison between IL-17 and combined TNF-alpha/IL-17 induced genes in primary murine hepatocytes
por: Sparna, Titus, et al.
Publicado: (2010)

TNFα sensitizes neuroblastoma cells to FasL-, cisplatin- and etoposide-induced cell death by NF-κB-mediated expression of Fas
por: Galenkamp, Koen MO, et al.
Publicado: (2015)

Fas/FasL mediates NF-κBp65/PUMA-modulated hepatocytes apoptosis via autophagy to drive liver fibrosis
por: Tan, Siwei, et al.
Publicado: (2021)

The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability
por: Henkler, Frank, et al.
Publicado: (2005)

LiCl induces TNF-α and FasL production, thereby stimulating apoptosis in cancer cells
por: Kaufmann, Larissa, et al.
Publicado: (2011)

Involvement of Fas/FasL pathway in the murine model of atopic dermatitis
por: Bień, Karolina, et al.
Publicado: (2017)

The Fas/FasL System in Reproduction: Survival and Apoptosis
por: Mor, Gil, et al.
Publicado: (2002)

Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes
por: Coe, Genevieve L., et al.
Publicado: (2016)

Role of the Fas/FasL pathway in HIV or SIV disease
por: Poonia, Bhawna, et al.
Publicado: (2009)

Heat stress decreases egg production of laying hens by inducing apoptosis of follicular cells via activating the FasL/Fas and TNF-α systems
por: Li, Gui-Ming, et al.
Publicado: (2020)

Antiinflammatory Effects of CD95 Ligand (FasL)-induced Apoptosis
por: Gao, Yakun, et al.
Publicado: (1998)

In vivo Effects in Melanoma of ROCK Inhibition-Induced FasL Overexpression
por: Teiti, Iotefa, et al.
Publicado: (2015)

Naja atra Cardiotoxin 1 Induces the FasL/Fas Death Pathway in Human Leukemia Cells
por: Chiou, Jing-Ting, et al.
Publicado: (2021)

Fas/FasL Contributes to HSV-1 Brain Infection and Neuroinflammation
por: Krzyzowska, Malgorzata, et al.
Publicado: (2021)

Enhancing Production and Cytotoxic Activity of Polymeric Soluble FasL-Based Chimeric Proteins by Concomitant Expression of Soluble FasL
por: Morello, Aurore, et al.
Publicado: (2013)

Systemic FasL and TRAIL Neutralisation Reduce Leishmaniasis Induced Skin Ulceration
por: Tasew, Geremew, et al.
Publicado: (2010)

Palmitoylation of human FasL modulates its cell death-inducing function
por: Guardiola-Serrano, F, et al.
Publicado: (2010)

FasL microgels induce immune acceptance of islet allografts in nonhuman primates
por: Lei, Ji, et al.
Publicado: (2022)

The Role of Fas-FasL Signaling Pathway in Induction of Apoptosis in Patients with Sulfur Mustard-Induced Chronic Bronchiolitis
por: Pirzad, Gila, et al.
Publicado: (2010)

Cadmium-induced apoptosis in neuronal cells is mediated by Fas/FasL-mediated mitochondrial apoptotic signaling pathway
por: Yuan, Yan, et al.
Publicado: (2018)

Associations of serum soluble Fas and Fas ligand (FasL) with outcomes in systemic lupus erythematosus
por: Vincent, Fabien B, et al.
Publicado: (2020)

Modulation of SIV and HIV DNA Vaccine Immunity by Fas-FasL Signaling
por: Yan, Jiabin, et al.
Publicado: (2015)

The signaling pathways by which the Fas/FasL system accelerates oocyte aging
por: Zhu, Jiang, et al.
Publicado: (2016)

Dual Role of Fas/FasL-Mediated Signal in Peripheral Immune Tolerance
por: Yamada, Akiko, et al.
Publicado: (2017)

Involvement of the TNF and FasL Produced by CD11b Kupffer Cells/Macrophages in CCl(4)-Induced Acute Hepatic Injury
por: Sato, Atsushi, et al.
Publicado: (2014)

FasL Modulates Expression of Mmp2 in Osteoblasts
por: Svandova, Eva, et al.
Publicado: (2018)

Human FasL Gene Is a Target of β-Catenin/T-Cell Factor Pathway and Complex FasL Haplotypes Alter Promoter Functions
por: Wu, Jianming, et al.
Publicado: (2011)

Low concentrations of doxycycline attenuates FasL-induced apoptosis in HeLa cells
por: Yoon, Jung Mi, et al.
Publicado: (2015)

HSV-2 Regulates Monocyte Inflammatory Response via the Fas/FasL Pathway
por: Krzyzowska, Malgorzata, et al.
Publicado: (2013)

Genetic Polymorphisms of Fas/FasL Promoter Associated with Hepatitis C cirrhosis and HCC
por: Abed, Sally, et al.
Publicado: (2017)

Fas/FasL pathway and cytokines in keratinocytes in atopic dermatitis – Manipulation by the electromagnetic field
por: Szymanski, Lukasz, et al.
Publicado: (2018)

Elevated Concentrations of Soluble Fas and FasL in Multiple Sclerosis Patients with Antinuclear Antibodies
por: Sremec, Josip, et al.
Publicado: (2020)

Correction: Involvement of the TNF and FasL Produced by CD11b Kupffer Cells/Macrophages in CCl(4)-Induced Acute Hepatic Injury
Publicado: (2014)

D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway
por: Tian, Hua, et al.
Publicado: (2017)

FasL Is Required for Osseous Healing in Extraction Sockets in Mice
por: Apaza Alccayhuaman, Karol Alí, et al.
Publicado: (2021)

Hepatocyte Nuclear Factor (HNF)‐4α Induces Expression of Endothelial Fas Ligand (FasL) to Prevent Cancer Cell Transmigration: A Novel Defense Mechanism of Endothelium against Cancer Metastasis
por: Osanai, Makoto, et al.
Publicado: (2002)

Role of Fas/FasL in regulation of inflammation in vaginal tissue during HSV-2 infection
por: Krzyzowska, M, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_las2b276qjcb0kmq90iq5i27n5