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Lipotoxicity and β Cell Maintenance in Obesity and Type 2 Diabetes

Obesity and diabetes are often associated with lipotoxic conditions in multiple tissues. The insulin-producing β cells are susceptible to elevated lipid levels and the ensuing lipotoxicity. The preservation of β cell mass and function is one of the main goals of diabetes management under these metab...

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Detalles Bibliográficos
Autores principales: Ye, Risheng, Onodera, Toshiharu, Scherer, Philipp E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391718/
https://www.ncbi.nlm.nih.gov/pubmed/30834357
http://dx.doi.org/10.1210/js.2018-00372