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Lipotoxicity and β Cell Maintenance in Obesity and Type 2 Diabetes
Obesity and diabetes are often associated with lipotoxic conditions in multiple tissues. The insulin-producing β cells are susceptible to elevated lipid levels and the ensuing lipotoxicity. The preservation of β cell mass and function is one of the main goals of diabetes management under these metab...
Autores principales: | Ye, Risheng, Onodera, Toshiharu, Scherer, Philipp E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391718/ https://www.ncbi.nlm.nih.gov/pubmed/30834357 http://dx.doi.org/10.1210/js.2018-00372 |
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