Dural lymphatics regulate clearance of extracellular tau from the CNS

BACKGROUND: Alzheimer’s disease is characterized by two main neuropathological hallmarks: extracellular plaques of amyloid-β (Aβ) protein and intracellular aggregates of tau protein. Although tau is normally a soluble monomer that bind microtubules, in disease it forms insoluble, hyperphosphorylated...

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Detalles Bibliográficos
Autores principales: Patel, Tirth K., Habimana-Griffin, LeMoyne, Gao, Xuefeng, Xu, Baogang, Achilefu, Samuel, Alitalo, Kari, McKee, Celia A., Sheehan, Patrick W., Musiek, Erik S., Xiong, Chengjie, Coble, Dean, Holtzman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391770/
https://www.ncbi.nlm.nih.gov/pubmed/30813965
http://dx.doi.org/10.1186/s13024-019-0312-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391770/
https://www.ncbi.nlm.nih.gov/pubmed/30813965
http://dx.doi.org/10.1186/s13024-019-0312-x

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