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Controlling Epithelial Polarity: A Human Enteroid Model for Host-Pathogen Interactions

Human enteroids—epithelial spheroids derived from primary gastrointestinal tissue—are a promising model to study pathogen-epithelial interactions. However, accessing the apical enteroid surface is challenging because it is enclosed within the spheroid. We developed a technique to reverse enteroid po...

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Detalles Bibliográficos
Autores principales: Co, Julia Y., Margalef-Català, Mar, Li, Xingnan, Mah, Amanda T., Kuo, Calvin J., Monack, Denise M., Amieva, Manuel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391775/
https://www.ncbi.nlm.nih.gov/pubmed/30811997
http://dx.doi.org/10.1016/j.celrep.2019.01.108