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Time dependent response of daunorubicin on cytotoxicity, cell cycle and DNA repair in acute lymphoblastic leukaemia

BACKGROUND: Daunorubicin is commonly used in the treatment of acute lymphoblastic leukaemia (ALL). The aim of this study was to explore the kinetics of double strand break (DSB) formation of three ALL cell lines following exposure to daunorubicin and to investigate the effects of daunorubicin on the...

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Detalles Bibliográficos
Autores principales: Al-Aamri, Hussain Mubarak, Ku, Heng, Irving, Helen R., Tucci, Joseph, Meehan-Andrews, Terri, Bradley, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391779/
https://www.ncbi.nlm.nih.gov/pubmed/30813936
http://dx.doi.org/10.1186/s12885-019-5377-y