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Identification of transcription factor binding sites using ATAC-seq

Transposase-Accessible Chromatin followed by sequencing (ATAC-seq) is a simple protocol for detection of open chromatin. Computational footprinting, the search for regions with depletion of cleavage events due to transcription factor binding, is poorly understood for ATAC-seq. We propose the first f...

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Detalles Bibliográficos
Autores principales: Li, Zhijian, Schulz, Marcel H., Look, Thomas, Begemann, Matthias, Zenke, Martin, Costa, Ivan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391789/
https://www.ncbi.nlm.nih.gov/pubmed/30808370
http://dx.doi.org/10.1186/s13059-019-1642-2